Gamasutra recently interviewed the producer and director of Resident Evil 5.  The RE series is reknowned for its high quality, and the previous installment in the series, RE4, was many folks' choice for Game of the Year in 2005.  Resident Evil 5 will be the first RE for next gen (or is it current gen?) systems, which is notable in and of itself.  However, RE5 will feature co-op gameplay, which is a first for the series (not counting the two player co-op in the lightgun style offshoot RE: Umbrella Chronicles).  You might expect co-op to be a last minute afterthought, merely tacked on to the primary single player experience for such a title.  However, in this interview, the creators state that this is NOT the case:

For Resident Evil 5, a lot of the elements in it are a refinement of things that we had in Resident Evil 4; making them better, and choosing which elements to keep, which elements to discard.

The biggest change that we had to it, and the biggest change that we had from when we first settled on the design for it, was that we definitely wanted to have co-op in it, right from the start, and to have co-op be an integral part of the game, just right from the start.

So that's one of the first things that we decided, when we were making the game. That has led the development of the game. Right now we're about 70% of the way through the development process.

RE4 was certainly a great game, and the creators indicate that they will not try to reinvent the wheel for the new game.  Throw tightly integrated co-op in, and you have a game that we here at Co-Optimus are definitely going to keep an eye on.

This will be a day one pick up for me. I have been waiting for this game for a long time...pretty much since the first Resident Evil came out. I always dreamed of working my way through the mansion with a friend.

March can't come soon enough!

Ditto

Sounds great to me; should keep me interested in the game much longer than just one play-through.

I see noone remembers the OutBreak series... It's a bit of a shame, I think those were the best Resident Evil games, cuz they had 4 player Coop!!!
They were the first Resident Evil games to have Coop play, not Umbrella Chronicles...
I wish they could remake it with System Link as an option... Or they could port it to PC and have LAN servers and stuff.

I'm a latecomer to the RE series, and didn't know about the Outbreak series. Thanks for the info, I will edit that in.

I almost started played Resident Evil when the first Outbreak was released...but the lack of mic support kept me from buying it.

You don't know what you missed txshurricane... It was great fun playing with 4 players, because one player could push a button, and that opens a door at some point, the other goes in...etc...etc. Hehh... there were some interesting things like only one player could see something. For example: You were going into a building, and the viewpoint showed a zombie going in front of the camera, but only you have seen it, nobody else (tried it). And it didn't need Mic support, that was the phun!
And thanks for putting me into the news, wanna help you much more with everything I can

I see noone remembers the OutBreak series... It's a bit of a shame, I think those were the best Resident Evil games, cuz they had 4 player Coop!!!
They were the first Resident Evil games to have Coop play, not Umbrella Chronicles...
I wish they could remake it with System Link as an option... Or they could port it to PC and have LAN servers and stuff.

You don't know what you missed txshurricane... It was great fun playing with 4 players, because one player could push a button, and that opens a door at some point, the other goes in...etc...etc. Hehh... there were some interesting things like only one player could see something. For example: You were going into a building, and the viewpoint showed a zombie going in front of the camera, but only you have seen it, nobody else (tried it). And it didn't need Mic support, that was the phun!
And thanks for putting me into the news, wanna help you much more with everything I can