| Game Name | Release Date | Platform |
|---|---|---|
| Destroy All Humans! 2 | 2006-10-02 | Playstation 2 |
| Destroy All Humans! 2 | 2006-10-02 | Xbox |
| Destroy All Humans: Big Willy Unleashed | 2008-02-26 | Wii |
| Destroy All Humans! 2 | 2016-11-29 | PlayStation 4 |
| Destroy All Humans! – Clone Carnage | 2022-05-31 | Xbox One |
| Destroy All Humans! – Clone Carnage | 2022-05-31 | PlayStation 4 |
| Destroy All Humans! – Clone Carnage | 2022-06-01 | PC |
| Destroy All Humans! 2 - Reprobed | 2022-08-30 | PC |
| Destroy All Humans! 2 - Reprobed | 2022-08-30 | Xbox Series |
| Destroy All Humans! 2 - Reprobed | 2022-08-30 | PlayStation 5 |