Dead Rising 4 has a co-op campaign mode that is separate from the story mode. The co-op mode supports up to four players and tasks them with completing various challenges and trials within Willamette Mall. The co-op mode spreads these out across a number of episodes. Completing one episode unlocks the next. Skills are separate from the single-player game, and there is a special "Multiplayer" tree added
Frank is back in Willamette, Colorado, 16 years after the events of the original Dead Rising. A mysterious outbreak has overrun the Willamette Memorial Megaplex Mall and surrounding town with deadly predators… and Frank soon realizes that what’s dead doesn’t always stay that way.
As Frank seeks to uncover the truth behind the outbreak, he faces new undead enemies, including the Fresh – newly zombified victims that will turn in front of his eyes, and exhibit superior speed and ferocity. He also has to tangle with the Evo – zombies with superior strength and mobility that mimic the behavior of predatory hunting animals.
Additionally, several fan-favorite Dead Rising features return, including the ability to combine hundreds of weapons and vehicles to combat the horde – ranging from the practical, to the practically insane. Frank also gets access to all-new EXO Suits, giving him super-strength and incredible firepower, as well as the ability to rip down objects in the world to use as weapons. From giant pipes to parking meters, the world is filled implements of mass zombie destruction.